Association of Factor V Leiden With Subsequent Atherothrombotic Events
نویسندگان
چکیده
منابع مشابه
the association of coagulation factor v (leiden) and factor ii (prothrombin) mutations with stroke
conclusions the prevalence of both fv and fii variants are population based. iran is an ethnically diverse country. therefore, for a comprehensive analysis of a potential association of fv and/or fii mutations with stroke among iranian population, epidemiological studies could be conducted among different ethnic groups. patients and methods the study population consisted of 153 patients of diff...
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BACKGROUND Factor V Leiden (FVL) supposedly carries relatively higher risk of deep vein thrombosis (DVT), compared to the risk of pulmonary embolism (PE). AIM To prove this paradox in a group of patients with various clinical presentation of venous thromboembolism (VTE). MATERIALS AND METHODS We retrospectively evaluated clinical pattern of VTE in patients who had been referred to vascular ...
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Livedoid vasculopathy is a rare chronic relapsing disorder characterised by recurrent painful thrombotic and vasculitic ulcers on the legs. We present the cases of two Indian women with livedoid vasculopathy that were found to be associated with an underlying factor V Leiden heterozygous mutation. There were no other thrombotic manifestations, and livedoid vasculopathy was the sole presenting f...
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Thrombophilia is a multigenic disease in which the combination of genetic polymorphisms increases the risk of deep vein thrombosis (DVT). The rapid identification of these genetic combinations requires high-throughput analysis of single nucleotide polymorphisms (SNPs). The TaqMan fluorogenic 5'-->*3' nuclease assay (PE/Applied Biosystems, Foster City, CA) with custom-designed primers, probes an...
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Background: Factor V Leiden, Prothrombin gene (G20210A) and MTHFR (C677T) polymorphism are the main biomarkers for evaluation of tendency for venous thromboembolism. We aimed to investigate the frequency of mutations in factor V Leiden, Prothrombin G20210A and MTHFR C677T and identify the genetic status for these mutations in patients with venous thrombosis. Methods: This study was carried out...
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ژورنال
عنوان ژورنال: Circulation
سال: 2020
ISSN: 0009-7322,1524-4539
DOI: 10.1161/circulationaha.119.045526